role

Clinical Senior Lecturer and Honorary Consultant, Paediatric Liver, GI and Nutrition Centre, King’s College London School of Medicine at King’s College Hospital.

qualifications

MB BCh BAO (Hons), University College Dublin, June 1999
Irish Medical Council: Full Registration July 2000 (No. 22952)
Entered on the Register of Medical Specialists (Ireland) November 2007
General Medical Council: Full Registration March 2006 (No. 6142549)
Entered on the Register of Medical Specialists (Paediatrics), February 2009
Membership Royal College of Physicians of Ireland (MRCPI Paediatrics) 2002
Doctorate in Medicine (MDRes) King’s College London January 2012

research project title(s)

Cellular therapy of liver disease: hepatocyte transplantation and the potential of mesenchymal stem cells
Non-invasive assessment of liver disease in children
Non-alcoholic fatty liver disease in children: pathogenesis and biomarkers of disease

core expertise

Hepatocyte Biology
Hepatocyte Transplantation
Clinical Research

contact

Emer.Fitzpatrick@kcl.ac.uk

publications

Alginate microencapsulated hepatocytes optimised for transplantation in acute liver failure.
Jitraruch S, Dhawan A, Hughes RD, Filippi C, Soong D, Philippeos C, Lehec SC, Heaton ND, Longhi MS, Mitry RR.
PLoS One. 2014 Dec 1;9(12):e113609. doi: 10.1371/journal.pone.0113609. eCollection 2014. [pubmed]

Fitzpatrick E, Dhawan A. Noninvasive biomarkers in paediatric NAFLD; current status and glimpse of the future. Accepted World Journal Gastroenterology 2014

Fitzpatrick E, Cotoi C, A Quaglia, M Ford-Adams, N Hadzic. Mauriac Hepatopathy; a retrospective review from a tertiary centre. Ach Dis Child 2014 Jan 10 http://www.ncbi.nlm.nih.gov/pubmed/24412980 (epub ahead of print)

Fitzpatrick E, Wu Y, Dhadda P, Hughes RD, Mitry RR, Qin H, Lehec SC, Heaton ND, Dhawan A. Co-culture with mesenchymal stem cells results in improved viability and function of human hepatocytes Cell Transplantation Oct 2013 (epub ahead of print)

Kronstein V, Fitzpatrick E, Baker A. Management of cholestatic pruritis in paediatric patients with Alagille syndrome. Journal of Pediatric Gastroenterology, Hepatology and Nutrition 2013; 57(2) 149-56

Leonis MA, Alonso EM, Im K, Belle SH, Squires RH, et al; the Pediatric Liver Failure Study Group. Chronic acetaminophen exposure in pediatric acute liver failure. Pediatrics 2013; 1331(3):e740 – 6

Fitzpatrick E, Dew TK, Quaglia A, Sherwood RA, Mitry RR, Dhawan A. Analysis of adipokine concentrations in paediatric non-alcoholic fatty liver disease. Pediatr Obes. 2012; 7(6):471-9.

Fitzpatrick E, Quaglia A, Vimalesvaran S, Basso MS, Dhawan A. Transient Elastography Is A Useful Non-Invasive Tool For The Evaluation of Fibrosis In Paediatric Chronic Liver Disease. J Pediatr Gastroenterol Nutr. 2012; 56(1):72-76

Blomme B, Fitzpatrick E, Quaglia A, De Bruyne R, Dhawan A, Van Vlierberghe H. Serum protein N-glycosylation in paediatric non-alcoholic fatty liver disease.Pediatr Obes. 2012; 7(2):165-73.

Fitzpatrick E, Mitry R, deBruyne R, Quaglia A, Hussain M, Dhawan A. Serum levels of CK18 M30 and leptin are useful predictors of steatohepatitis and fibrosis in Paediatric NAFLD. J Pediatr Gastroenterol Nutr. 2010; 51(4):500-6. PMID: 20808246

Fitzpatrick E, Jardine R, Farrant P, Karani J, Davenport M, Miele-Vergani G, Baker A. The predictive value of bile duct dimensions measured by ultrasound in neonates presenting with cholestasis. J Pediatr Gastroenterol Nutr. 2010; 51(1):55-60.PMID: 20543724

deBruyne R, Fitzpatrick E, Dhawan A. Fatty liver disease in children. Eat now pay later. Hepatol Int. 2010; 4(1):375-85. PMID: 20305757

Fitzpatrick E, Mitry RR, Dhawan A. Hepatocyte Transplantation: State of the Art. J Intern Med 2009; 266(4):399-57. PMID: 19765179

Fitzpatrick E, Mtega M, Dhawan A. Crigler Najjar Syndrome; therapeutic options and pharmacological consequences of deletions in the UGT1A1 complex. Expert Reviews Endocrinology and Metabolism. 2008; 3(6):725-737

Fitzpatrick E, Bourke B, Drumm B, Rowland M. The Incidence of Cyclic Vomiting Syndrome: Population-Based Study. Am J Gastroenterol 2008; 103(4):991-5 PMID: 18070235

Fitzpatrick E, Bourke B, Drumm B, Rowland M. Outcome for children with cyclical vomiting syndrome. Arch Dis Child 2007; 92(11):1001-4. PMID: 17588965

 

Book Chapters:

Practical Algorithms in Pediatric Gastroenterology 2014. Fitzpatrick E, Dhawan A. Hepatomegaly.

Practical Algorithms in Pediatric Gastroenterology 2014. Fitzpatrick E, Dhawan A. Neonatal Jaundice

 

[PubMed list  – main publications]